Saturday, May 30, 2020

New method to map cholesterol metabolism in brain

Researchers have developed new technology to monitor cholesterol in brain tissue which could uncover its relation to neurodegenerative disease and pave the way for the development of new treatments.

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A hormone -- plant style

Researchers have now found a method that might make the production of a biologically significant precursor of jasmonic acid more efficient and cheaper. Their innovation: they imitate how plants produce the hormone. The result is 12-OPDA, a central precursor of jasmonic acid. In the long term, it could also be a potential precursor for high-quality perfume.

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Wildfires can alter Arctic watersheds for 50 years

Climate change has contributed to the increase in the number of wildfires in the Arctic and can dramatically shift stream chemistry. Researchers at the University of New Hampshire have found that some of the aftereffects, like decreased carbon and increased nitrogen, can last up to five decades and could have major implications on vital waterways like the Yenisei River and the Arctic Ocean

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New technology enables fast protein synthesis

Chemists have developed a protocol to rapidly produce protein chains up to 164 amino acids long. The flow-based technology could speed up drug development and allow scientists to design novel protein variants incorporating amino acids that don't occur naturally in cells.

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Gold mining with mercury poses health threats for miles downstream

Small-scale gold mining in the Peruvian Amazon poses a health hazard not only to the miners and communities near where mercury is used to extract gold from ore, but also to downstream communities hundreds of kilometers away where people eat mercury-contaminated river fish as part of their diet. Downstream children under 12 with the highest levels of mercury in their bodies were found to have lost IQ points and become anemic.

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Immune landscape of multiple brain cancers charted

A new study has profiled, in a sweeping comparative analysis, the distinct immune landscapes of tumors that arise in the brain, or gliomas, and those that metastasize to the organ from the lungs, breast and skin.

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Paid sick leave mandates hold promise in containing COVID-19

Mandates like those found in the federal government's Families First Coronavirus Response Act may be helping to slow the pandemic.

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